MSTP Publications
2007 MSTP Graduates
Current MSTP Students
2008 MSTP Graduates
During their tenure, University of Chicago MSTP students publish in a variety of peer-reviewed journals and other publications. Below are publications of our 2008 MSTP graduates during their MSTP tenure.
Daniel Clayburgh, MD, PhD, Pathology
Clayburgh DR, Yoon JD, Cipriani NA, Ricketts PA, Arora VM. (2008) Collateral Damage. N Engl J Med. 359(10):1048-54.
Clayburgh DR, Musch MW, Leitges M, Fu YX, Turner JR. (2006) Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. J Clin Invest. 116(10):2682-94
Graham WV, Wang F, Clayburgh DR, Cheng JX, Yoon B, Wang Y, Lin A, Turner JR. (2006) Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. J Biol Chem. 281(36):26205-15
Blair SA, Kane SV, Clayburgh DR, Turner JR. (2006) Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Lab Invest. 86(2):191-201.
Robert Guzy, MD, PhD, Cell Physiology
Guzy R.D., Mack M.M., Schumacker P.T. Mitochondrial Complex III is required for hypoxia-induced ROS production and gene transcription in yeast. Antioxid Redox Signal. (2007) Sep;9(9):1317-28.
Iwase H., Robin E., Guzy R.D., Mungai P.T., Vanden Hoek T.L., Chandel N.S., Levraut J., Schumacker P.T. Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Free Radic Biol Med. (2007) Aug 15;43(4):590-9.
Robin E., Guzy R.D., Loor G., Iwase H., Waypa G.B., Marks J.D., Vanden Hoek T.L., Schumacker P.T. Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion. J Biol Chem. (2007) Jun 29;282(26):19133-43.
Waypa G.B., Guzy R., Mungai P.T., Mack M.M., Marks J.D., Roe M.W., Schumacker P.T. Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circ Res. (2006) Oct 27;99(9):970-8.
Guzy R.D. and Schumacker P.T. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Experimental Physiology (2006) Sep;91(5):807-19. Review.
Ali Javaheri, MD, PhD, Molecular Genetics & Cell Biology
McSherry T, Kitazono A, Javaheri A, Kron SJ, Mueller P. "Non-catalytic Function for ATR in the Checkpoint Response." Cell cycle . (In press).
Wysocki R*, Javaheri A*, Kristjansdottir K, Sha F, Kron SJ. "CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage." Nature Structural & Molecular Biology - 13, 908 - 914 (2006)
*These authors contributed equally to this work
Javaheri A, Wysocki R, Jobin-Robitaille O, Altaf M, Côté J, Kron SJ. "Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci USA 103, 13771–13776 (2006)
Kao J, Milano MT, Javaheri A, Garofalo MC, Chmura SJ, Weichselbaum RR, Kron SJ. "gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy." Curr Cancer Drug Targets 3, 197-205 (2006)
Jennifer Pogoriler, MD, PhDCancer Biology
Pogoriler J, Millen K, Utset M, Du W. (2006) Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development. Oct; 133(19):3929- 37.
Du, W, Pogoriler, J. (2006) Retinoblastoma family genes. Oncogene. Aug 28;25(38):5190-200.
Paul VanderLaan, MD, PhD, Pathology
VanderLaan PA, Reardon CA, Sagiv Y, Blachowicz L, Lukens J, Nissenbaum M, Wang CR, Getz GS. Characterization of the natural killer T-cell response in an adoptive transfer model of atherosclerosis. Am J Pathol. 2007;170:1100-1107.
Current MSTP Students
MSTP trainees produced over 43 peer reviewed publications and invited reviews and book chapters during the 2009-09 academic year. The below listing is not inclusive but a selected sample. Of those, MSTP trainees were first or second author in 80% of those cited.
Peer Reviewed Journals
Markus Boos, Immunology
Boos, M., K. Ramirez and B. Kee. 2007. Extrinsic and Intrinsic Regulation of Early Natural Killer Cell Development. Immunologic. Rev. In press.
Boos, M., Y. Yokota, G. Eberl and B. Kee. 2007. Mature Natural Killer Cell and Lymphoid Tissue Inducing Cell Development Requires Id2-Mediated Suppression of E-protein Activity. J. Exp. Med. 204:1119-1130.
Jonathan Budzik, Microbiology
Budzik JM, Marraffini LM, Schneewind O.Assembly of pili on the surface of Bacillus cereus vegetative cells Mol. Microbiol. 2007. In press
Stephanie Graves, Cancer Biology
El Andaloussi A, Graves S, Meng F, Mandal M, Mashayekhi M, Aifantis I. Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus. Nat Immunol. 2006 Apr;7(4):418-26.
Robert Hsieh, Biochemistry & Molecular Biology
Molecular Characterization of a B-ring Unsaturated Estrogen: Implications for Conjugated Equine Estrogen Components of Premarin. Robert W. Hsieh, Shyamala S. Rajan, Sanjay K. Sharma and Geoffrey L. Greene. Steroids, 2007, (In Press).
Identification of Ligands with Bicyclic Scaffolds Provides Insights into Mechanisms of Estrogen Receptor Subtype Selectivity. Robert W. Hsieh, Shyamala S. Rajan, Sanjay K. Sharma, Yuee Guo, Eugene R. DeSombre, Milan Mrksich and Geoffrey L. Greene. Journal of Biological Chemistry, 281(26), 17909-19, (2006).
Martin King, Medical Physics
M King, X Pan, L Yu, and M Giger, “Region-of-interest reconstruction of motion-contaminated data using a weighted backprojection filtration algorithm”, Med. Phys., 33 (2006) 1222-1238.
M King, M Giger, K Suzuki, and X Pan, “Feature-based characterization of motion-contaminated calcified plaques in cardiac multidetector CT”, Med Phys (accepted).
M King, M Giger, K Suzuki, D Bardo, B Greenberg, L Lan, and X Pan, “Computerized assessment of motion-contaminated calcified plaques in cardiac multidetector CT”, Med Phys (In press).
Jennifer Lanning, Pathology
Qahwash IM, Boire A, Lanning J, Krausz T, Pytel P, Meredith SC. Site-specific effects of peptide lipidation on beta -amyloid aggregation and cytotoxicity. J Biol Chem. 2007 Aug 9. (In press).
Atul Mallik, Neurobiology
Zhang JX, Rosenberg A, Mallik AK, Husson TR, Issa NP. The representation of complex images in spatial frequency domains of primary visual cortex. J Neurosci. 2007 Aug 29;27(35):9310-8.
Husson TR, Mallik AK, Zhang JX, Issa NP. Functional imaging of primary visual cortex using flavoprotein autofluorescence. J Neurosci. 2007 Aug 8;27(32):8665-75.
Kent Mouw, Biochemistry& Molecular Biology
Mouw, K.W., Rice, P.A. “Shaping the Borrelia burgdorferi genome: crystal structure and binding properties of the DNA-bending protein Hbb”. Mol Micro. 65, 1319-1330.
Cara Rabik, Molecular Genetics & Cell Biology
Rabik, C.A. and M.E. Dolan. Molecular mechanisms of resistance and toxicity associated with platinating agents. Cancer Treatment Reviews, 33(1): 9-23, 2007.
Rabik, C.A., Njoku, M.C., Dolan, M.E. Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance cancer chemotherapy. Cancer Treatment Reviews, 32(4): 261-276, 2006.
Fishel, M.L., Rabik, C.A., Bleibel, W.K., Li, X., Moschel, R.C., Dolan, M.E. Role of GADD34 in Modulation of Cisplatin Cytotoxicity. Biochemical Pharmacology, 71(3): 239-47, 2006.
Kelly Riordan, Microbiology
Bill Blaylock, Kelly E. Riordan, Dominique M. Missiakas, Olaf Schneewind. Characterization of the Yersinia enterocolitica type III secretion ATPase YscN and its regulator, YscL. Bacteriol. 2006 May;188(10):3525-34
Talya Salant, History of Culture
Salant T, Lauderdale DS. Impact of incidental bilateral salpingo-oophorectomy in a family member on breast cancer risk assessment: clinical considerations. Cancer Detect Prev. 2006;30(4):329-32.
Salant T, Ganschow PS, Olopade OI, Lauderdale DS. "Why take it if you don't have anything?" breast cancer risk perceptions and prevention choices at a public hospital. J Gen Intern Med. 2006 Jul;21(7):779-85.
Salant T, Santry HP. Internet marketing of bariatric surgery: contemporary trends in the medicalization of obesity. Soc Sci Med. 2006 May;62(10):2445-57.
Douglas Stoller, Cell Physiology
Stoller, DA, R Kakkar, M Smelley, K Chalupsky, JU Earley, NQ Shi, JC Makielski, EM McNally. Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress. Journal of Molecular and Cellular Cardiology . (In Press).
Kakkar, R, B Ye, DA Stoller, M Smelley, NQ Shi, K Galles, M Hadhazy, JC Makielski, and EM McNally. Spontaneous coronary vasospasm in KATP mutant mice arises from a smooth muscle extrinsic process. Circulation Research March 17, 2006. 98(5):682-9.
Benjamin Thompson, Immunology
Thompson BJ, Buonamici S, Sulis ML, Palomero T, Vilimas T, Basso G, Ferrando A, Aifantis I. The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia. J Exp Med. 2007 Aug 6;204(8):1825-35.
Emre Turer, Immunology
Ma A, Turer E.E2 enzymes: expanding the 'ubi-verse' of immune signaling.Nat Immunol. 2006 Sep;7(9):903-4.
Gregory Vlacich, Molecular Genetics & Cell Biology
Vlacich G, Roe C, Webb GC. Technology insight: microarrays-- research and clinical applications. Nat Clin Pract Endocrinol Metab. 2007 Aug;3(8):594-605
Invited Review and Book Chapters
Eric Vikingstad, Medical Physics
George KP, Vikingstad EM, Silbergleit R, Cao Y. Brain imaging in aphasia. In: Medical Speech-Language Pathology: A Practitioner's Guide, 2nd Edition. Johnson AF, Jacobson BH, editors. New York: Thieme; 2007.
Amber Martell, Computational Neuroscience
Van Drongelen, W., Martell, A., Lee, H.C. Neocortical Epileptiform Activity in Neuronal Models with Biophysically Realistic Ion Channels. In Computational Neuroscience in Epilepsy (2007). Soltesz, I. and Staley, K. (Eds.) Elsevier in review.
Selene Koo, Structural Biology
Koo, S., Novak, T., Piccirilli, J.A. Catalytic Mechanism of the HDV Ribozyme. In Ribozymes and RNA Catalysis; Lilley, D. and Eckstein, F., Eds.; Royal Society of Chemistry: Cambridge; 92-122 (In press).
