MSTP | Recent PhD Theses

Biochemistry & Molecular Biology

MSTP Trainee Faculty Advisor(s) Thesis Title
Kathryn Scherpelz Stephen Meredith Alzheimer's Brain and Meninges-Seeded Amyloid Fibrils
Jeremy Treger Francisco Bezanilla Novel Techniques in Optical Electrophysiology Lead to New Biophysical Insights
Ian Roundtree Chuan He Post-Transcriptional Gene Regulation by N 6-Methyladenosine and Selective RNA Binding Proteins
Katherine Zhou Tao Pan RNA Modifications: Impact on Protein Binding, Co-Transcriptional Regulation, and Sequencing Signatures

Biophysics

MSTP Trainee Faculty Advisor(s) Thesis Title
Alan Hutchison Aaron Dinner Improved statistical methods for analyzing circadian rhythms in high-throughput data
Gabe Salzman Demet Arac-Ozkan/Shohei Koide The Extracellular Regions of Adhesion G Protein-Coupled Receptors Regulate Ligand Binding and Intracellular Signaling
Ramya Parameswaran Bozhi Tian Silicon nanowires for the optical modulation of cellular activity

Cancer Biology

MSTP Trainee Faculty Advisor(s) Thesis Title
Adam Gasser Stephen Meredith Synthesis and Assembly of Functionalized Peptide Nanoplatforms for the Targeted Delivery of Molecules to Tumors
Marina Sharifi Kay Macleod Autophagy is Required for Focal Adhesion Dissassembly, Tumor Cell Motility, and Metastasis
Erin Mowers Kay Macleod The role of autophagy in tumor progression and metastasis

Computational Neuroscience

MSTP Trainee Faculty Advisor(s) Thesis Title
Arup Sarma David Freedman Learning-Dependent Plasticity of Visual and Cognitive Encoding in Parieto-Frontal Networks
Sophia Uddin Howard Nusbaum Auditory understanding of speech and non-speech

Development, Regeneration & Stem Cell Biology

MSTP Trainee Faculty Advisor(s) Thesis Title
Rajiv Nadadur Ivan Moskowitz Defining Gene Regulatory Networks of Cardiac Rhythm

Ecology & Evolution

MSTP Trainee Faculty Advisor(s) Thesis Title
Sylvia Ranjeva Sarah Cobey/Greg Dwyer Host heterogeneity and the dynamics of pathogen diversity.
Frank Wen Sarah Cobey Ecological and Evolutionary Dynamics of Influenza Shaped by Human Immunity

Human Genetics

MSTP Trainee Faculty Advisor(s) Thesis Title
David Blair Andrey Rzhetsky Investigating Complex and Mendelian Disease Genetics Through Massive Digital Phenotyping
Samantha Thomas Yoav Gilad Induced Pluripotent Stem Cells as a Model to Study Individual Variation and Comparative Genomics

Genetics, Genomics & Systems Biology

MSTP Trainee Faculty Advisor(s) Thesis Title
Justin Chew Mike Rust Vulnerability to Molecular Noise Constrains the Architecture of Bacterial Clocks

Immunology

MSTP Trainee Faculty Advisor(s) Thesis Title
Melissa Tjota Anne Sperling Activation of Antigen Presenting Cells through FCRGamma Drives IL-33 Dependent TH2-Type Responses in the Lungs
Tony Tu Yang-Xin Fu CD160, An Essential Regulator of the Cytokine Response by Natural Killer Cells
Jennifer Jacobsen Barbara Kee EZH2 Regulates the Pre-antigen Receptor Checkpoint and B-2 Lineage Commitment
Ben Casterline Julie Wardenburg Early life acquisition and pathogenesis of maternally inherited Bacteroides fragilis
Jeff Bunker Albert Bendelac Specificity of homeostatic IgA
Phil Hsu Chuan He Roles of mRNA methylations in biology: processing and development

Integrative Neuroscience

MSTP Trainee Faculty Advisor(s) Thesis Title
Anya Bershad Harriet de Wit Effects of Opioids on Social and Emotional Processing in Humans

Microbiology

MSTP Trainee Faculty Advisor(s) Thesis Title
Russell Becker Julie Bubeck-Wardenburg Tissue-Specific Modulation of Innate Immunity by Staphylococcus aureus Alpha-Toxin
Vivian Choi Julie-Bubeck-Wardenburg Characterization of Virulence-Associated Protein Processing Genes in Bacteroides fragilis
Mark Lunderberg Olaf Schneewind Assembly of the Bacillus anthracis vegetative cell envelope
Megan Zilla Dominique Missiakas The Role of LytR-CpsA-Psr Enzymes in the Lifecycle of Bacillus anthracis

Neurobiology

MSTP Trainee Faculty Advisor(s) Thesis Title
Iboro Umana Dan McGehee Nicotinic Modulation of Descending Pain Control Circuitry
David Koren Wei Wei Dendritic Mechanisms Underlying Retinal Direction Selectivity

Public Policy

MSTP Trainee Faculty Advisor(s) Thesis Title
Nina Gao David Meltzer What Gets Measured (Gets Done): Essays on Healthcare, Policy and Perils of the Subjective made Objective